China’s CanSinoBIO says COVID-19 shot may be less effective over time, booster shot promising

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BEIJING — China’s CanSino Biologics Inc. said the efficacy rate for its single-dose COVID-19 vaccine may fall over time although it should still have a rate of 50% or more five to six months after inoculation.

A second shot given to trial participants six months after their first injection could offer substantial protection, Zhu Tao, CanSinoBIO’s chief scientific officer, said in an online presentation late on Wednesday.

“A booster shot six months later led to a seven times to 10-times increase in neutralizing antibody levels, so we expect in this case efficacy could reach over 90%,” Zhu said, though he cautioned more clinical trial data was needed for more precise estimates….

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