New embryo models offer hope for research on miscarriages, birth defects

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Scientists have generated early-stage human embryo models that could help shed light on the “black box” of initial human development stages and improve research on pregnancy loss and birth defects.

Two separate teams found different ways to produce versions of a blastocyst — the pre-embryonic mass of cells at the stage of development around five days after a sperm fertilizes an egg — potentially opening the door for a huge expansion of research.

The scientists make clear that the models differ from human blastocysts and are not capable of developing into embryos. But their work comes as new ethical guidelines on such research are being drafted and could spark fresh debate.

Keep on reading: New embryo models offer hope for research on miscarriages, birth defects